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Methaqualone, sold under the brand name Quaalude and sometimes stylized "Quaalude" in the United States and Mandrax in the United Kingdom and South Africa, is a sedative and hypnotic medication. It is a member of the quinazolinone class.
The sedative-hypnotic activity of methaqualone was first noted by researchers in the 1950s. In 1962, methaqualone was patented in the US by Wallace and Tiernan. Its use peaked in the early 1970s as a hypnotic, for the treatment of insomnia, and as a sedative and muscle relaxant.
Methaqualone became increasingly popular as a recreational drug and club drug in the late 1960s and 1970s, known variously as "ludes" or "sopers" (also "soaps") in the U.S. and "mandrakes" and "mandies" in the UK, Australia and New Zealand.